I was the Lupron Depot shot five years ago and I have never been the same since. I have really long cycles up to 38 days, muscles and bone pain, hard time concentrating, systemic yeast infections, swollen lymph nodes, migraines, nausea, depression, extreme acne, severe IBS, etc. I am trying to find out if anyone has these particular symptoms or can relate to this problem.
I was falsly diagnosed with endometriosis. My new doctors confirm that I do not have it and I didn’t need to be on the Lupron for nine months.

Could the problem be due to endometriosis? Is that why you had the Lupron to begin with?

From my personal research, I have found that swollen lymph nodes have nothing to do with my period. How about severe hormones fluctuations? Or systemic yeast infections causing them to become irritated? I have had this problem for ten years since I was on Lupron for 9 months straight. I highly do not recommened this drug. Can this be lymphatic cancer? Or some kind of syndrome? Or abnoramilty? PLEASE HELP!!!
I have been seeing doctors for strange PMS problems since age 17. No answers yet. I did research the long term side affects of the drug Lupron Depot. I have a lot of these symptoms even 5 years after being on this medication. No matter what caused the problem in the first place. How to solve it is my question? Or can it be solve? maybe not.

This could be related to hormone fluctuations going on. I would recommend checking with your doctor as well to see what they say.

I have been having some pain during intercourse. The information I have researched identifies it as secondary (arising after a pain free period) superficial entrance (only upon entrance into the vagina) pain. I was sexually mistreated (not sure I’d use the word "abuse") by my last partner, but my new partner is a great man. I was diagnosed with bacterial vaginosis and a systemic yeast infection (not candidiasis), but both of those have been cleared up for a few months. The articles I have read list sexual trauma, recurrent yeast infections, and sexual infection as possible causes, but now that all three have been cleared up (the trauma resolved by me leaving him), I don’t know what the problem could be. I feel fine once he’s inside me, but it hurts tremendously (like a tearing, significantly worse than when I lost my virginity) when he is entering me. Fingers and tampons pose no problems. When I got my pap smear done nothing showed up as abnormal and the speculum was not painful. What is going on with my body?

you might be tensing up inside cause you know what is going to happen when it goes in. try to relax and think about something else. i had a similar problem a few months ago and for no reason at all it hurt like pins and needles and really tight when he was inside of me. i put it off for a week or so and then it gradually got better. just work around intercourse for now and take your time. i hope this helps!

I have been having some pain during intercourse. The information I have researched identifies it as secondary (arising after a pain free period) superficial entrance (only upon entrance into the vagina) pain. I was sexually mistreated (not sure I’d use the word "abuse") by my last partner, but my new partner is a great man. I was diagnosed with bacterial vaginosis and a systemic yeast infection (not candidiasis), but both of those have been cleared up for a few months. The articles I have read list sexual trauma, recurrent yeast infections, and sexual infection as possible causes, but now that all three have been cleared up (the trauma resolved by me leaving him), I don’t know what the problem could be. I feel fine once he’s inside me, but it hurts tremendously (like a tearing, significantly worse than when I lost my virginity) when he is entering me. Fingers and tampons pose no problems. When I got my pap smear done nothing showed up as abnormal and the speculum was not painful. What is going on with my body?
I am plenty lubricated and we used lubricants hoping they would help. They didn’t.

You mention being mistreated by your last partner… most likely what you are experiencing is a result of anxiety due to that; and since once you’re engaged in sex, the pain stops. I suggest using a water based lubricant to avoid the initial roughness.

It will take you some time to build trust with your new partner, but once you do, your pain will most likely stop.

Polycystic Ovarian Syndrome
Irritable Bowel Syndrome
Leaky Gut
Social Anxiety and Avoidant Personality Disorder
Severe, Chronic Candidiasis/Fungemia (a systemic yeast infection of the blood and all orfices, that is very serious)
Chronic Fatigue with a suppressed immune system
Hirsutism
Delayed Sleep Phase Syndrome
Incontience
and Panic Attacks

???

These are all symptoms of a pituitary/adrenal disorder. Hirsutism, panic attacks, chronic fatigue, GI symptoms, problem with sleep, immune problems point to adrenal problems either caused by problems with your pituitary (which regulates adrenals) or directly from adrenals. Have your cortisol levels checked…preferrably by an Endocrinologist with pituitary expertise.

What symptoms did you experience? How can you find out for sure if that’s what it is, and what’s the best way to get rid of it?

bgroves, Candida albicans is a fungal (YEAST) organism that is present in everyone’s intestinal tract. It is normally kept under control by the immune system and by beneficial intestinal bacteria. This balance is upset when these bacteria are destroyed (typically by antibiotics), or when our immune function is impaired.

Once that balance is upset, Candida begins to proliferate and invade and colonize our body tissues. It most commonly appears as a vaginal yeast infection or as oral thrush. But Candida albicans can also spread inside the body and become a systemic problem.

Systemic candidiasis can be divided into 2 primary syndromes: candidemia and disseminated candidiasis (organ infection by Candida species). Deep organ infections due to Candida species are generally observed as part of the disseminated candidiasis syndromes and may involve one or more organs.

Candidemia
Candida species are currently the fourth most commonly isolated organism in blood cultures, and Candida infection is generally considered a nosocomial infection. The patient’s history commonly reveals the following:
Several days of fever that is unresponsive to broad-spectrum antimicrobials; frequently the only marker of infection
Prolonged intravenous catheterization
A history of several key risk factors (see Pathophysiology)
Possibly associated with multiorgan infection
Physical examination results may include the following:
Fever
Macronodular skin lesions (approximately 10%)
Candidal endophthalmitis (approximately 10-28%)
Occasionally, septic shock (hypotension, tachycardia, tachypnea)
Other causes of candidemia without invasive disease include the following:
Intravascular catheter-related candidiasis: This entity usually responds promptly to catheter removal and antifungal treatment.
Suppurative thrombophlebitis: This is associated with prolonged central venous catheterization. Suppurative thrombophlebitis manifests as fever and persistent candidemia despite appropriate antifungal therapy and catheter removal. Sepsis and septic shock may develop.
Endocarditis: The frequency of endocarditis has recently increased. Candida species, primarily C albicans and Candida parapsilosis (>60% of cases), are the most common cause of fungal endocarditis. The aortic and mitral valves are most commonly involved. The endocarditis may be exogenous (due to direct inoculation during surgery) or endogenous (due to hematogenous dissemination during bloodstream invasion. Candida endocarditis is associated with 4 main risk factors, including intravenous heroin use (frequently associated with C parapsilosis infection), chemotherapy, prosthetic valves (approximately 50%), and prolonged use of central venous catheters. The physical examination reveals a broad range of manifestations, including fever unresponsive to antimicrobials, hypotension, shock, new or changing murmurs, and large septic emboli to major organs, a characteristic of fungal endocarditis.
Disseminated candidiasis: This is frequently associated with multiple deep organ infections or may involve single organ infection. Unfortunately, blood cultures are negative in up to 40-60% of patients with disseminated candidiasis. The history of a patient with presumptive disseminated candidiasis reveals a fever unresponsive to broad-spectrum antimicrobials and negative results from blood culture. Physical examination reveals fever (may be the only symptom) with an unknown source and associated sepsis and septic shock.

Successful therapy for serious systemic Candida infections requires initiation of antifungal therapy as early as possible, as soon as adequate culture results are obtained.

Different classes of antifungals are now available to manage any type of candidal infection. Azoles, fluconazole in particular,22 have become the mainstay of therapy over the past few years. These include topical and systemic agents. Posaconazole is the most recent addition to this group of antifungals. Polyenes include amphotericin B, liposomal amphotericin B formulations, and topical nystatin. Allylamines include terbinafine, which is formulated in a topical preparation and an oral tablet. The newest group of antifungals is echinocandins, including caspofungin, micafungin, and anidulafungin. Because of the excellent clinical efficacy of echinocandins, low incidence of adverse events, good safety profile, and ease of use, these agents may revolutionize the management of candidal infections in the near future.

Is this possible at all…? Some sources on the internet say it is, some say it isn’t…but I’ve learned not to take any medical advice too seriously unless it’s come from a medical professional.
I’m finally getting it treated but it’s been a while, and I’m just a bit worried it might have spread. I’ll be talking to the doctor anyway about it, so no worries.

Yes, it is possible, thought I wouldn’t worry about it if I were you. It’s not like your vaginal yeast infection is going to spread to your heart. You have yeast elsewhere in the body.
Here’s half an article on the subject:

Systemic yeast / Candida?
by Marcelle Pick, OB/GYN NP

In this article, Marcelle Pick, OB/GYN NP explains what Candida yeast is, the symptoms of systemic yeast infection, the digestion problems associated with Candida yeast, and how to treat it, including instructions for a yeast-free diet.

… … …

What is systemic yeast (Candida)?
Candida albicans is a fungal organism that is present in everyone’s intestinal tract. It is normally kept under control by the immune system and by beneficial intestinal bacteria.

This balance is upset when these bacteria are destroyed (typically by antibiotics), when our immune function is impaired (typically due to stress or illness), or when we develop environmental or food sensitivities.

Once that balance is upset, Candida begins to proliferate and invade and colonize our body tissues. It most commonly appears as a vaginal yeast infection or as oral thrush. But Candida albicans can also spread inside the body and become a systemic problem.

How does Candida albicans affect the body?
When Candida proliferates, it changes from its simple, relatively harmless form to an invasive form, with long root-like structures that penetrate the intestinal lining. Penetration can break down the boundary between the intestinal tract and the circulatory system. This may allow introduction into the bloodstream of many substances which may be systemic allergens, poisons, or irritants. Partially digested proteins may enter the blood through the openings created by Candida (called leaky gut syndrome), which explains why individuals with Candida also often display a variety of food and environmental allergies.

What are some of the symptoms of Candida yeast infections?
While many of these symptoms may be caused by conditions other than candidiasis, a woman suffering from systemic yeast will typically experience a number of the following symptoms:

Generalized: Fatigue, lethargy, migraine headaches, weakness, dizziness, sensory disturbances, hypoglycemia, muscle pain, respiratory problems, chemical sensitivities.

Gastrointestinal: Oral thrush, diarrhea, constipation, rectal itching, inflammatory bowel disease (IBD), flatulence, food sensitivities.

Genitourinary: Yeast vaginitis, menstrual and premenstrual problems, bladder inflammation, chronic urinary tract infections (UTI’s), bladder inflammation, cystitis, PMS.

Dermatological: Eczema, acne, hives.

Mental and emotional: Confusion, irritability, memory loss, inability to concentrate, depression, insomnia, learning disability, short attention span.

Autoimmune: Multiple sclerosis, arthritis, systemic lupus erythematosus, myasthenia gravis, scleroderma, hemolytic anemia, sarcoidosis, thrombocytopenic purpura.

Diagnosis of systemic yeast (Candida) infection
A simple stool test can be done to determine if someone has Candida yeast overgrowth. If there are food sensitivities, a special blood test such as an ALCAT or RAST panel is done to identify reactive foods. This is important because while food allergies are easily noted, it’s more difficult to pinpoint the cause of food sensitivity since the reaction can take 8–72 hours.

Polycystic Ovarian Syndrome
Irritable Bowel Syndrome
Leaky Gut
Social Anxiety and Avoidant Personality Disorder
Severe, Chronic Candidiasis/Fungemia (a systemic yeast infection of the blood and all orfices, that is very serious)
Chronic Fatigue with a suppressed immune system
Hirsutism
Delayed Sleep Phase Syndrome
Incontience
and Panic Attacks

???

These are all symptoms of a pituitary/adrenal disorder. Hirsutism, panic attacks, chronic fatigue, GI symptoms, problem with sleep, immune problems point to adrenal problems either caused by problems with your pituitary (which regulates adrenals) or directly from adrenals. Have your cortisol levels checked…preferrably by an Endocrinologist with pituitary expertise.

I have had a yeast infection nonstop for 3 years now. It never went away. Not once. Now I’m scared that I might have sepsis or a systemic yeast infection. I know that candida can get into the bloodstream but I don’t know if that’s happened to me.

What can I do to make my yeast infection go away? My gyno gave me two Diflucan, that didn’t work. Then the last time I went to him he said I didn’t have a yeast infection but HE’S WRONG because I STILL have it. He was in a rush to get home and didn’t want to bother with me. I still have all of the symptoms, discharge, etc. I STILL have it trust me on this one.

Please help me! I’m so scared.

First of all, if you have had this for three years and your doctor hasnt schooled you on this, then you need to get yourself a GYN will cares enough to treat you, educate you and be there to listen to your concerns.

Now, like another lady said before, just because you have a discharge, does not mean you have a yeast infection. It can be just normal discharge, the vaginas way of cleaning itself.

Do you always feel itchy and discomfort??

I know its a little too much, but for the sake of making a connection I will share. I discharge quite often myself. At first I was scared it was some type of STD or infection. My doc did a biopsy, where they clip a small piece of tissue from inside of you to test (considering your problem, you should have had a biopsy already). Turns out, my body just discharges alot. Sometimes its clear with an egg yolk like consistency, and other times it is white, and at some point in the month, it will be a very pale yellow. All as it turns out to be quite normal.

Now, if it is indeed a yeast, stay away from sweets. Are you on any antibiotics? Antibio can also cause yeast infections.

There is this product I bough over the counter it costed me about 18. Its called RePhresh. (Exactly how i spelled it). It is supposed to help with your PH balance in th vagina. If you maintain a good PH balance, then your vagina will be healthier. Try RePhresh as see if it makes any difference for you. It is not a cure for anything, just a helpful product for women who have problems down there.

Schedule yourself with another doctor and sit and explain all your concerns. Make a list of questions so you can ask the doc when you go.

Good Luck.

single dose (one pill) really cure it..I thought they used internal creams like monistat..

I was given one refill..am I supposed to take this. If so, when. I was told nothing by the doctor as could not reach the nurse and the front desk checked and said that was why she was calling me and called the prescription in..but noone told me anything.

I did not have any symptoms of a yeast infection (discharge, itching) so how will I know when it is gone or if this one dose is effective..it was detected apparently when they did a pap smear.

Also if someone had systemic candidiasis, would this get rid of it.

Also what side effects might I expect..I got diarrhea soon after taking..is it likely from that and since it is in my blood for several days, will I continue to have this diarrhea several days.

Fluconozole works better and more quickly for a lot of women without the mess of creams. You take the first pill now and the second one in four days. Its very common for a pap to show yeast or bacterial vaginosis (BV) even if you are not having symptoms. However, that being said, if you are not having any symptoms it’s your choice to take the meds. You can hold on to them in case you do start to show symptoms. I’ve never heard a patient complain of side effects from fluconozole, and I’ve take it without any side effects, but you can read the literature that came along with it or ask your pharmasist or doctor about possible side effects.